How does Spironolactone work for Acne? The drug Spironolactone is a medication used to treat acne. It increases the sex hormone binding globulin (SHBG) and decreases the intensity and length of breakouts. In addition, it regulates oil production and blocks androgen receptors.
Reduces the intensity and lifespan of hormonal breakouts
Although it has been a long time since my teenage years, I still remember my pre-teen acne days. A hormonal induced outbreak can be a painful and downright embarrassing rite of passage. Luckily, there are plenty of products on the market designed specifically to treat hormonal skin conditions. If you are not ready to commit to a treatment program, you can always try out an over the counter (OTC) topical ointment. Be sure to use caution, as this type of topical ointment may have a short shelf life.
One thing to watch out for is using the wrong brand of ointment. Similarly, be sure to consult your doctor before making a final decision. This is especially true if you are pregnant or breastfeeding. In some cases, you may need to use an ointment containing a different active ingredient.
Blocks androgen receptors
One of the more popular ways of treating acne is with Spironolactone, an androgen receptor blocker. This treatment has shown some positive results in both men and women. However, it can take months to see results.
Acne is caused by a number of factors, including the presence of dirt and bacteria in the pores of the skin. The oil glands in the skin trap these substances in the pores, thereby producing excess sebum. A hormone called dihydrotestosterone (DHT) triggers the release of sebum. If the oil glands produce too much sebum, they clog the pores, resulting in acne.
Spironolactone is one of several anti-androgen treatments. Other types include cyproterone acetate and flutamide. Both of these medications work by blocking androgen receptors. In addition, they also inhibit oil gland function.
Increases sex hormone binding globulin (SHBG)
Sex hormone binding globulin (SHBG) plays a role in the transport of sex hormones throughout the bloodstream. The globulin has different affinities for estrogen and testosterone. This has implications for how the hormones are bioavailable.
SHBG levels can vary from person to person, depending on many factors. Some may be hereditary or related to a specific condition. However, the amount of SHBG in the blood is usually not used to make a diagnosis. A blood test will typically be ordered when a patient has symptoms of sex hormone imbalance.
Higher SHBG levels have been associated with improved cardiovascular health in postmenopausal women. The hormone is also known to reduce the risk of estrogen-induced cancer growth.
Several studies have been conducted on the levels of SHBG in relation to metabolic syndrome. One study examined a SNP in the SHBG gene, rs1799941, that is associated with type 2 diabetes. Another looked at the association between SHBG and insulin resistance.
Side effects
Spironolactone is a medication that is used for treating high blood pressure and other conditions. It is also used to treat acne and hair loss in women. There are many medications that can cause side effects, so be sure to talk with your doctor before taking it.
Spironolactone is available in both brand name and generic forms. The generic version is usually less expensive.
When taken as prescribed, spironolactone has shown excellent results. It may be prescribed in a single dose, or in two or more divided doses. You should never take more than the recommended dose, or you may experience unwanted side effects.
Spironolactone is an oral prescription drug that works by blocking the effects of the aldosterone hormone. Aldosterone is one of the factors that causes acne.
